Piroctone Olamine

Piroctone Olamine, also known under the brand name `Octopirox´, is a compound that has a similar effect on dandruff as the well-known ingredient Ketoconazole.

 Studies on the effectiveness of Octopirox show that it also stimulates hair growth and helps against hereditary hair loss. Dandruff and seborrheic dermatitis can cause hair loss and thinning hair. Dandruff and seborrheic dermatitis are caused by the Malassezia globose. This is a single cell fungus on the skin that occurs only on the scalp. Most of the times, the problem will not go away on its own and requires continues treatment.

Piroctone Olamine is one of the active ingriendients in the Neofollics Shampoo.

Piroctone Olamine compared to Ketoconazole

Both ingredients were compared in a study with 150 men who suffer from hereditary hair loss and dandruff. The 150 subjects used a shampoo with 1% Ketoconazole or 1% Piroctone Olamine. They used the shampoo for 2 to 3 times a week for six months.

 Both treatments show a reduction in itching and dandruff after 2 to 6 weeks. The effect of the treatments on various hair growth parameters is as follows (in percentages):

– The severity of hair loss decreases (Ketoconazole: -17.3%, Piroctone Olamine -16,5%)
– The percentage of hairs in the anagen (growth) phase increases (Ketoconazole 4.9%, Piroctone Olamine 7.9%)
– The effect on the hair diameter increased (Ketoconazole 5.4%, Piroctone Olamine 7.7%)

So the study shows that Piroctone Olamine scores better in a numer of areas in comparison to Ketoconazole:

– Compared to Ketoconazole, it ensures an increase in number of hairs in the anagen (growth) phase by more then 10% in 33% of people.

– It gives 88% of the people thicker hair, despite hereditary hair loss, whereby this is 78% with Ketoconazole.

– It gives a significant increase of the air diameter with 34%. Compared to Ketoconazole giving it 28%.

– The severity of hair loss decreases (Ketoconazole: -17.3%, Piroctone Olamine -16,5%) – The percentage of hairs in the anagen (growth) phase increases (Ketoconazole 4.9%, Piroctone Olamine 7.9%)

– The effect on the hair diameter is increased (Ketoconazole 5.4%, Piroctone Olamine 7.7%)


The above results show that Piroctone Olamine works effectively against dandruff and itching and stimulates hair growth in multiple ways. It stimulates hair growth by decreasing hair loss, increasing the number of hairs in the growth phase and increasing the hair diameter. When compared to the well-known ingredient Ketoconazole, it has a similar effect on itch and dandruff and scores better when it comes to hair growth. That is why we at Neofollics are using this ingredient as one of the active ingredients in our shampoos.

Hair Growth Stimulating Shampoo

The Neofollics Hair Growth Stimulating Shampoo is the most effective shampoo to promote hair growth. In addition to the 12 hair growth stimulating ingredients, this shampoo is also nourishing. It soothes the scalp, is effective against dandruff and lays the foundation for healthy hair growth.

The Neofollics Shampoo is applied directly to the scalp by the fingertips. Here the shampoo is gently massaged and distributed. In conclusion, the shampoo provides rich nutrients to the scalp that are absorbed by the hair follicles.

Frequently asked questions

Pierard-Franchimont, C.Goffin, V.Henry, F. Uhoda, I. Braham, C. Pierard, G.E.(2002). Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% Piroctone Olamine and 1% zinc pyrithione formulations. International journal of Cosmetic Science, 2002, 24, 249-256

The Neofollics Hair Growth Stimulating Shampoo bevat 1% Piroctone Olamine.

If you experience dandruff or thinning hair. A Piroctone Olamine Shampoo might help you combat this. As explained above Piroctone Olamine has a positive effect on the hair growth as well as combatting dandruff.

There are close to no side-effects to a Piroctone Olamine shampoo. The only side effect is that a shampoo with Piroctone Olamine or Ketoconazole can dry out the hair. We advise to use the Neofollics Conditioner to nourish the hair.

High-quality products are of great importance to us. So you will find no harmful substances such as SLS and other sulfates, silicones and parabens in our products.



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